The effect of whole-body vibration in osteopenic patients after total knee arthroplasty: a randomized controlled trial

Author: Zhao He#1, Jiao Zheng#2, Shengfu Liu#3, Zhiqiang Guan#4, Qiyun Zhou1, Xiao Jin5, Zhiyuan Guan6
Affiliation: <sup>1</sup> Department of Orthopedics, Qinghai Provincial People&#39;s Hospital, Qinhai, China. <sup>2</sup> Department of Anorectal, Xuzhou Municipal Hospital Affiliated with Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People&#39;s Republic of China. <sup>3</sup> Department of Orthopedics, The Shanghai Tenth People&#39;s Hospital of Tongji University, Shanghai, People&#39;s Republic of China. <sup>4</sup> Department of Rheumatology and Immunology, Xuzhou Municipal Hospital Affiliated with Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People&#39;s Republic of China. 1650574233@qq.com. <sup>5</sup> Department of Rheumatology and Immunology, Xuzhou Municipal Hospital Affiliated with Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People&#39;s Republic of China. jinxiao202122@163.com. <sup>6</sup> Department of Orthopedics, The Shanghai Tenth People&#39;s Hospital of Tongji University, Shanghai, People&#39;s Republic of China. gzq199207@163.com.
Conference/Journal: Aging Clin Exp Res
Date published: 2022 Jan 14
Other: Special Notes: doi: 10.1007/s40520-021-02043-2. , Word Count: 205


Background:
Total knee arthroplasty (TKA) is an important treatment for knee osteoarthritis, but the result of whole-body vibration (WBV) in knee function rehabilitation and bone loss with osteopenia was unknown. Therefore, the purpose of this study is to study whether low-frequency, low-amplitude WBV can improve the clinical outcome of knee osteoarthritis.

Methods:
This study was randomized and included 67 osteopenic patients (55-90 years, 85% women) for TKA surgery (control group N = 32, WBV group N = 35). All selected patients after TKA surgery tested clinical results, such as knee function and bone mass in baseline, 3 months after surgery, and 6 months after surgery.

Results:
Compared to the control group, the WBV group improved pain scores, thigh circumference, lower limb muscle strength, joint activity, and joint function in 6 months after surgery. WBV intervention also improves bone density in the spine, the microstructure of the radius and tibia, and the bone turnover marker. At 3 months after TKA surgery, the WBV group had no significant effect on knee function and bone loss.

Conclusions:
Whole-body vibration for osteopenic patients with knee arthroplasty showed good therapeutic results in 6 months after TKA surgery, but the long-term therapeutic effect still needs to be further observed.

Keywords: Knee arthroplasty; Osteoarthritis; Osteopenia; Whole-body vibration.

PMID: 35028919 DOI: 10.1007/s40520-021-02043-2