Author: Ali Albarrati1, Mohammed Taher1,2, Rakan Nazer3
Affiliation: <sup>1</sup> Department of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. <sup>2</sup> Faculty of Physical Therapy, Cairo University, Egypt. <sup>3</sup> Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Conference/Journal: J Diabetes
Date published: 2021 Apr 1
Other: Volume ID: 13 , Issue ID: 4 , Pages: 292-298 , Special Notes: doi: 10.1111/1753-0407.13106. , Word Count: 226
Type 2 diabetes mellitus (T2DM) is usually associated with respiratory manifestations including inspiratory muscle weakness which affects exercise capacity. The present study aimed to determine the effect of inspiratory muscle training (IMT) on inspiratory muscle strength and exercise capacity in patients with Type 2 diabetes mellitus (T2DM).
This was a randomized controlled trial in patients with type 2 diabetes mellitus with no previous cardiopulmonary or neuromuscular diseases. Patients had no back pain. Patients were randomized into interventional or placebo groups. Sniff nasal inspiratory pressure (SNIP), maximum inspiratory pressure (MIP), and six-minute walking test (6MWT) were measured at baseline and 8 weeks post incremental inspiratory muscle training.
At baseline, interventional and placebo groups were similar in age, body mass index, sex inspiratory muscle strength, and exercise capacity. After 8 weeks of incremental inspiratory muscle training at 40% of MIP, the interventional group had a significant increase in the SNIP (mean difference: 18.5 ± 5.30 cm H2O vs 2.8 ± 4.8 cm H2O) and MIP (mean difference: 19.4 ± 4.3 Vs 5.4 ± 3.6 cm H2O) compared to the placebo group, respectively. The interventional group showed improvement in the 6MWT (mean difference: 70 ± 29 m vs 34 ± 24 m) compared to the placebo group, P < .05.
Incremental inspiratory muscle training increased the diaphragm strength in patients with T2DM and improved exercise capacity.
Keywords: 2型糖尿病; functional capacity; inspiratory muscle training; randomized clinical trial; respiratory muscle strength; type 2 diabetes mellitus; 功能能力; 吸气肌训练; 呼吸肌力; 随机临床试验.
PMID: 33471439 DOI: 10.1111/1753-0407.13106