Author: Song Gao1, Keneilwe Kenny Kaudimba1, Jiaxin Cai1, Yao Tong1,2, Qianqian Tian1, Peize Liu1, Tiemin Liu1,3, Peijie Chen1, Ru Wang1
Affiliation: <sup>1</sup> Shanghai Key Laboratory for Human Athletic Ability Development and Support, School of Kinesiology, Shanghai University of Sport, Shanghai, China.
<sup>2</sup> Institute of Sport Science, Shenyang Sport University, Shenyang, China.
<sup>3</sup> State Key Laboratory of Genetic Engineering, Department of Endocrinology and Metabolism, School of Life Sciences, Institute of Metabolism and Integrative Biology, Human Phenome Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Conference/Journal: Front Neurol
Date published: 2021 Jan 13
Other:
Volume ID: 11 , Pages: 615861 , Special Notes: doi: 10.3389/fneur.2020.615861. , Word Count: 362
Introduction: With an increasing number of China's aging population, Parkinson's disease (PD) increases year by year. Persons with PD exhibit abnormal balance functions, leading to motor skills difficulties, such as unstable walking or even falling. Therefore, activities of daily living and quality of life are affected. This study aims to explore the effectiveness of Tai Chi training based on the mobile phone app in improving the balance ability of persons with PD. Methods and Analysis: A randomized, single-blind, parallel controlled trial will be conducted in this study. One hundred forty-four persons with PD who meet the inclusion criteria will be randomly divided into a 1:1:1 ratio: (1) control group, (2) basic experimental group (basic app with no Tai Chi training features), and (3) balanced-enhanced experimental group (basic app with Tai Chi training features). Individuals with PD will be evaluated on balance and motor function outcomes. The primary outcome measure is the limits of stability (including the maximum excursion and direction control); the secondary outcome measures include the Unified Parkinson's Disease Rating Scale III (UPDRS-III), Berg Balance Scale (BBS), Functional Reach Test (FRT), Timed Up & Go (TUG), 6-Minute Walk Test (6MWT), and 39-item Parkinson's Disease Questionnaire (PDQ-39). Each group of patients will go through an assessment at baseline, 17 and 33 weeks. Discussion: This study will evaluate the effectiveness of the mobile phone app Tai Chi training on the balance function of persons with PD. We assume that a challenging Tai Chi project based on a mobile phone app will improve balance in the short and long term. As walking stability progresses, it is expected that daily activities and quality of life improve. These findings will be used to improve the effectiveness of future home management measures for persons with PD. Ethics and Dissemination: This study has been approved by the ethical review committee of the Shanghai University of Sport (approval number: 102772019RT056). Informed consent will be obtained from all participants or their guardians. The authors intend to submit the study findings to peer-reviewed journals or academic conferences to be published. Clinical Trial Registration: Chinese Clinical Trial Registry (ChiCTR2000029135).
Keywords: Parkinson's disease; Tai Chi training; balance ability; mobile phone app; randomized controlled trial.
PMID: 33519695 PMCID: PMC7838616 DOI: 10.3389/fneur.2020.615861