Author: He M1, Sun M1, van Wijk E2, van Wietmarschen H3, van Wijk R4, Wang Z5, Wang M6, Hankemeier T1, van der Greef J7
Affiliation: <sup>1</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Leiden University, LACDR, Department of Analytical Biosciences, P.O. Box 9502, 2300 RA Leiden, The Netherlands.
<sup>2</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Leiden University, LACDR, Department of Analytical Biosciences, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Meluna Research, Geldermalsen, The Netherlands. Electronic address: eduard.vanwijk@sinodutchcentre.nl.
<sup>3</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; TNO Innovation for Life, P.O. Box 360, 3700 AJ, Zeist, The Netherlands.
<sup>4</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Meluna Research, Geldermalsen, The Netherlands.
<sup>5</sup>Changchun University of Chinese Medicine, Changchun 130117, PR China.
<sup>6</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Leiden University, LACDR, Department of Analytical Biosciences, P.O. Box 9502, 2300 RA Leiden, The Netherlands; TNO Innovation for Life, P.O. Box 360, 3700 AJ, Zeist, The Netherlands; SU BioMedicine/TNO, P.O. Box 360, 3700 AJ, Zeist, The Netherlands.
<sup>7</sup>Sino Dutch Centre for Preventive and Personalized Medicine, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands; Leiden University, LACDR, Department of Analytical Biosciences, P.O. Box 9502, 2300 RA Leiden, The Netherlands; TNO Innovation for Life, P.O. Box 360, 3700 AJ, Zeist, The Netherlands.
Conference/Journal: Complement Ther Med.
Date published: 2016 Apr
Other:
Volume ID: 25 , Pages: 20-6 , Special Notes: doi: 10.1016/j.ctim.2015.12.015. Epub 2016 Jan 2. , Word Count: 181
To present the possibilities pertaining to linking ultra-weak photon emission (UPE) with Chinese medicine-based diagnostics principles, we conducted a review of Chinese literature regarding UPE with respect to a systems view of diagnostics. Data were summarized from human clinical studies and animal models published from 1979 through 1998. The research fields can be categorized as follows: (1) human physiological states measured using UPE; (2) characteristics of human UPE in relation to various pathological states; and (3) the relationship between diagnosis (e.g., Chinese syndromes) and the dynamics of UPE in animal models. We conclude that UPE has clear potential in terms of understanding the systems view on health and disease as described using Chinese medicine-based diagnostics, particularly from a biochemistry-based regulatory perspective. Linking UPE with metabolomics can further bridge biochemistry-based Western diagnostics with the phenomenology-based Chinese diagnostics, thus opening new avenues for studying systems diagnostics in the early stage of disease, for prevention-based strategies, as well as for systems-based intervention in chronic disease.
Copyright © 2015 Elsevier Ltd. All rights reserved.
KEYWORDS: Chinese medicine research; Diagnosis; Reactive oxygen species (ROS); Ultra-weak photon emission (UPE)
PMID: 27062943 DOI: 10.1016/j.ctim.2015.12.015