Author: Pace-Schott EF1, Amole MC2, Aue T3, Balconi M4, Bylsma LM2, Critchley H5, Demaree HA6, Friedman BH7, Gooding AEK6, Gosseries O8, Jovanovic T9, Kirby LAJ10, Kozlowska K11, Laureys S8, Lowe L12, Magee K6, Marin MF13, Merner A6, Robinson JL14, Smith RC15, Spangler DP7, Van Overveld M16, VanElzakker MB17
Affiliation: <sup>1</sup>Harvard Medical School, Boston, MA, USA. Electronic address: epace-schott@mgh.harvard.edu.
<sup>2</sup>University of Pittsburgh, Pittsburgh, PA, USA.
<sup>3</sup>University of Bern, Bern, Switzerland.
<sup>4</sup>Catholic University of Milan, Milan, Italy.
<sup>5</sup>University of Sussex, Sussex, UK.
<sup>6</sup>Case Western Reserve University, Cleveland, OH USA.
<sup>7</sup>Virginia Tech, Blacksburg, VA, USA.
<sup>8</sup>University of Liege, Liege, Belgium.
<sup>9</sup>Emory University, Atlanta, GA, USA.
<sup>10</sup>University of Texas at Tyler, Tyler, TX, USA.
<sup>11</sup>University of Sydney, Sydney, Australia.
<sup>12</sup>Neuroqualia (NGO), Truro, Nova Scotia, Canada.
<sup>13</sup>Université du Québec à Montréal, Montreal, Canada.
<sup>14</sup>Auburn University, Auburn, AL USA.
<sup>15</sup>Michigan State University, East Lansing, MI USA.
<sup>16</sup>Erasmus University Rotterdam, Rotterdam, the Netherlands.
<sup>17</sup>Massachusetts General Hospital, Boston, MA, USA.
Conference/Journal: Neurosci Biobehav Rev.
Date published: 2019 May 21
Other:
Pages: S0149-7634(18)30867-4 , Special Notes: doi: 10.1016/j.neubiorev.2019.05.002. [Epub ahead of print] , Word Count: 196
The role of peripheral physiology in the experience of emotion has been debated since the 19th century following the seminal proposal by William James that somatic responses to stimuli determine subjective emotion. Subsequent views have integrated forebrain's ability to initiate, represent and simulate such physiological events. Modern affective neuroscience envisions an interacting network of "bottom-up" and "top-down" signaling in which the peripheral (PNS) and central nervous systems both receive and generate the experience of emotion. "Feelings" serves as a term for the perception of these physical changes whether emanating from actual somatic events or from the brain's representation of such. 'Interoception' has come to represent the brain's receipt and representation of these actual and "virtual" somatic changes that may or may not enter conscious awareness but, nonetheless, influence feelings. Such information can originate from diverse sources including endocrine, immune and gastrointestinal systems as well as the PNS. We here examine physiological feelings from diverse perspectives including current and historical theories, evolution, neuroanatomy and physiology, development, regulatory processes, pathology and linguistics.
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
KEYWORDS: Autonomic Nervous System; Emotion; Emotion Regulation; Feelings; Insula; Interoception; Somatic Markers
PMID: 31125635 DOI: 10.1016/j.neubiorev.2019.05.002