Author: Wu C1, Yi Q2, Zheng X1, Cui S3, Chen B4, Lu L5, Tang C1
Affiliation: <sup>1</sup>Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong Province, P. R. China. <sup>2</sup>The First Clinical College, Guangzhou university of Chinese Medicine, Guangzhou, 510000, Guangdong Province, P. R. China. <sup>3</sup>Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, 518034, China. <sup>4</sup>The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. <sup>5</sup>Clinical Research Center, South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong Province, P. R. China.
Conference/Journal: J Am Geriatr Soc.
Date published: 2018 Dec 18
Other: Special Notes: doi: 10.1111/jgs.15714. [Epub ahead of print] , Word Count: 306
BACKGROUND/OBJECTIVES: Mind-body exercise has positive effects on cognitive performance, according to clinical observation and experts' recommendations. However, its potential benefits for the cognitive function of aging adults are uncertain and still lack systematic estimations. Therefore, we conducted a systematic review and meta-analysis to evaluate the overall efficacy and effectiveness of mind-body exercises for cognitive performance in aging individuals with or without cognitive impairment.
DESIGN: A systematic review and meta-analysis.
SETTING AND PARTICIPANTS: We searched related trials through June 2018 from four databases: Medline, Embase, PsycINFO (all via Ovid), and the Cochrane Library/Central Register of Controlled Trials.
MEASUREMENTS: Methodological quality was assessed using the Cochrane Risk of Bias Tool. A meta-analysis of comparative effects was performed using Review Manager v.5.3 software, and publication bias was examined using Egger's test.
RESULTS: A total of 32 randomized controlled trials with 3624 participants were ultimately included in this meta-analysis. The results revealed that mind-body exercises as a whole had benefits in improving global cognition compared with that of the control group (mean difference [MD] = 0.92; 95% confidence interval [CI] = 0.33-1.51; p = .002) and were more effective than control interventions in promoting cognitive flexibility (MD = -8.80; 95% CI = -15.22 to -2.38; p = .007), working memory (MD = 0.32; 95% CI = 0.01-0.64; p = .05), verbal fluency (standardized mean difference [SMD] = 0.27; 95% CI = 0.09-0.45; p = .003), and learning (SMD = 0.24; 95% CI = 0.10-0.39; p = .001) on cognitively intact or impaired older adults. In dose-subgroup analysis, only moderate exercise intensity (60-120 min per week) significantly increased global cognition scores compared with those of the control group (MD = 1.15; 95% CI = 0.34-1.97; p = .006).
CONCLUSION: Mind-body exercises, especially tai chi and dance mind-body exercise, are beneficial for improving global cognition, cognitive flexibility, working memory, verbal fluency, and learning in cognitively intact or impaired older adults. Moderate intensity is recommended as the optimal dose for older adults.
© 2018 The American Geriatrics Society.
KEYWORDS: cognitive impairment; cognitive performance; meta-analysis; mind-body exercises; older adults
PMID: 30565212 DOI: 10.1111/jgs.15714