Author: Gourine AV1, Ackland GL2
Affiliation: <sup>1</sup>Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London , London , United Kingdom.
<sup>2</sup>William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London , London , United Kingdom.
Conference/Journal: Physiology (Bethesda).
Date published: 2019 Jan 1
Other:
Volume ID: 34 , Issue ID: 1 , Pages: 71-80 , Special Notes: doi: 10.1152/physiol.00041.2018. , Word Count: 67
Lower resting heart rate and high autonomic vagal activity are strongly associated with superior exercise capacity, maintenance of which is essential for general well-being and healthy aging. Recent evidence obtained in experimental studies using the latest advances in molecular neuroscience, combined with human exercise physiology, physiological modeling, and genomic data suggest that the strength of cardiac vagal activity causally determines our ability to exercise.
PMID: 30540229 DOI: 10.1152/physiol.00041.2018