Effects of Music Intervention on the Physical and Mental Status of Patients with Breast Cancer: A Systematic Review and Meta-Analysis.

Author: Wang X1, Zhang Y1, Fan Y2,3,4, Tan XS5, Lei X2,3,4
Affiliation: <sup>1</sup>School of Pediatrics, Chongqing Medical University, Chongqing, China. <sup>2</sup>School of Public Health and Management, Chongqing Medical University, Chongqing, China. <sup>3</sup>Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, China. <sup>4</sup>Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, China. <sup>5</sup>Fifth Clinical College, Chongqing Medical University, Chongqing, China.
Conference/Journal: Breast Care (Basel).
Date published: 2018 Jul
Other: Volume ID: 13 , Issue ID: 3 , Pages: 183-190 , Special Notes: doi: 10.1159/000487073. Epub 2018 Jun 6. , Word Count: 194


Background: The aim of this review was to evaluate the effects of music intervention on the physical and mental status of patients with breast cancer.

Methods: 9 databases were searched; 30 randomized controlled trials that compared the effects of music plus standard care and standard care alone in patients with breast cancer were included. Methodological quality was assessed using the Jadad scale.

Results: The results of the meta-analysis suggested that music intervention was significantly effective in lowering systolic blood pressure (standardized mean difference (SMD) -0.63, 95% confidence interval (CI) -0.85 to -0.42; p < 0.00001), diastolic blood pressure (SMD -0.64, 95% CI -1.06 to -0.22; p = 0.003), and heart rate (SMD -0.45, 95% CI -0.66 to -0.24; p < 0.0001), and in relieving anxiety (Hamilton Scale: mean difference (MD) -7.04, 95% CI -9.31 to -4.78; p < 0.00001; Self-Rating Anxiety Scale: MD -7.40, 95% CI -10.28 to -4.52; p < 0.00001; State Anxiety Inventory: MD -12.40, 95% CI -21.86 to -2.94; p = 0.01), and depression (MD -7.39, 95% CI -8.35 to -6.43; p < 0.00001).

Conclusion: This review provides clues that music intervention might partially improve the physiological and psychological health of patients with breast cancer.

KEYWORDS: Breast neoplasms; Meta-analysis; Music intervention

PMID: 30069179 PMCID: PMC6062713 [Available on 2019-07-01] DOI: 10.1159/000487073