Integrative effect of yoga practice in patients with knee arthritis: A PRISMA-compliant meta-analysis.

Author: Wang Y1,2, Lu S2, Wang R3, Jiang P2, Rao F2,4, Wang B4, Zhu Y4, Hu Y4, Zhu J4,5
Affiliation: <sup>1</sup>School of Medicine, Nankai University, Tianjin. <sup>2</sup>Beijing Key Lab of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma &amp; War Injuries, PLA Institute of Orthopedics, Chinese PLA General Hospital, Beijing. <sup>3</sup>Department of Endocrinology, The Fourth Affiliated Hospital of Anhui Medical University. Hefei. <sup>4</sup>Department of Trauma and Orthopedics, Peking University People's Hospital, 11th Xizhimen South Street, Beijing. <sup>5</sup>Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Conference/Journal: Medicine (Baltimore).
Date published: 2018 Aug
Other: Volume ID: 97 , Issue ID: 31 , Pages: e11742 , Special Notes: doi: 10.1097/MD.0000000000011742. , Word Count: 206


BACKGROUND: Benefits of yoga practice in patients with knee osteoarthritis and rheumatoid arthritis remains controversial. This study performs a meta-analysis to quantify the efficiency of yoga exercise for patients pain reduction, functional recovery, and general wellbeing.

METHODS: A computerized search of PubMed and Embase was performed to identify relevant studies. The outcome measures were pain, stiffness, and physical function. Two investigators identified eligible studies and extracted data independently. The quality of citations was measured using Jadad score. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were calculated for pain, musculoskeletal impairment, quality of life, general wellbeing, and mental wellbeing.

RESULTS: A total of 13 clinical trials involving 1557 patients with knee osteoarthritis and rheumatoid arthritis were included in final meta-analysis with the average Jadad score 2.8. The SMD was -0.98 (95% CI -1.18, -0.78, P < .05) for pain, -1.83 (95% CI -2.09, -1.57, P < .05) for functional disability, was 0.80 (95% CI 0.59, 1.01, P < .05) for Short Form 36 Health Survey (SF-36) general health, 0.49 (95% CI 0.14, 0.82, P < .05) for SF-36 mental health, and HAQ was -0.55 (95% CI -0.83, -0.26, P < .05) for health associated questionnaire (HAQ). All the results favor yoga training group.

CONCLUSIONS: Regular yoga training is helpful in reducing knee arthritic symptoms, promoting physical function, and general wellbeing in arthritic patients.

PMID: 30075589 DOI: 10.1097/MD.0000000000011742