Effects of exercise-based cardiac rehabilitation in patients after percutaneous coronary intervention: A meta-analysis of randomized controlled trials.

Author: Yang X1,2, Li Y1,3, Ren X2,3, Xiong X1, Wu L2,3, Li J1, Wang J1, Gao Y2, Shang H2, Xing Y1
Affiliation: <sup>1</sup>Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China. <sup>2</sup>The Key Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China. <sup>3</sup>Beijing University of Chinese Medicine, Beijing 100029, China.
Conference/Journal: Sci Rep.
Date published: 2017 Mar 17
Other: Volume ID: 7 , Pages: 44789 , Special Notes: doi: 10.1038/srep44789. , Word Count: 203

In this study, we assessed the effect of rehabilitation exercise after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD). We performed a meta-analysis to determine the effects of exercise in patients after PCI. The Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, the Embase database, China National Knowledge Internet (CNKI), China Biology Medicine (CBM), and the Wanfang Database were searched for randomized controlled trials (RCTs). The key words used for the searches were PCI, exercise, walking, jogging, Tai Chi, and yoga. Six studies with 682 patients met our inclusion criteria; we chose the primary endpoint events of cardiac death, recurrence of myocardial infarction (MI), repeated PCI, coronary artery bypass grafting (CABG), and restenosis, and the secondary endpoint measures included recurrent angina, treadmill exercise (total exercise time, ST-segment decline, angina, and maximum exercise tolerance). The results showed that exercise was not clearly associated with reductions in cardiac death, recurrence of MI, repeated PCI, CABG, or restenosis. However, the exercise group exhibited greater improvements in recurrent angina, total exercise time, ST-segment decline, angina, and maximum exercise tolerance than did the control group. Future studies need to expand the sample size and improve the quality of reporting of RCTs.

PMID: 28303967 PMCID: PMC5356037 DOI: 10.1038/srep44789