Effects of whole-body vibration training on physical function, bone and muscle mass in adolescents and young adults with cerebral palsy.

Author: Gusso S1, Munns CF2, Colle P1, Derraik JG1, Biggs JB1, Cutfield WS1, Hofman PL1.
Affiliation: 1Liggins Institute, University of Auckland, Auckland, New Zealand. 2Endocrinology Department, The Children's Hospital at Westmead, Sydney, Australia.
Conference/Journal: Sci Rep.
Date published: 2016 Mar 3
Other: Volume ID: 6 , Pages: 22518 , Special Notes: doi: 10.1038/srep22518. , Word Count: 199


We performed a clinical trial on the effects of whole-body vibration training (WBVT) on muscle function and bone health of adolescents and young adults with cerebral palsy. Forty participants (11.3-20.8 years) with mild to moderate cerebral palsy (GMFCS II-III) underwent 20-week WBVT on a vibration plate for 9 minutes/day 4 times/week at 20 Hz (without controls). Assessments included 6-minute walk test, whole-body DXA, lower leg pQCT scans, and muscle function (force plate). Twenty weeks of WBVT were associated with increased lean mass in the total body (+770 g; p = 0.0003), trunk (+410 g; p = 0.004), and lower limbs (+240 g; p = 0.012). Bone mineral content increased in total body (+48 g; p = 0.0001), lumbar spine (+2.7 g; p = 0.0003), and lower limbs (+13 g; p < 0.0001). Similarly, bone mineral density increased in total body (+0.008 g/cm(2); p = 0.013), lumbar spine (+0.014 g/cm(2); p = 0.003), and lower limbs (+0.023 g/cm(2); p < 0.0001). Participants reduced the time taken to perform the chair test, and improved the distance walked in the 6-minute walk test by 11% and 35% for those with GMFCS II and III, respectively. WBVT was associated with increases in muscle mass and bone mass and density, and improved mobility of adolescents and young adults with cerebral palsy.

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