Author: Tao J1, Liu J2, Egorova N3, Chen X4, Sun S3, Xue X5, Huang J6, Zheng G2, Wang Q2, Chen L6, Kong J3.
Affiliation: 1College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China; Fujian Key Laboratory of Rehabilitation of Technology, Fuzhou, China; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. 2College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine , Fuzhou , China. 3Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA. 4The School of Social and Political Science, University of Edinburgh , Edinburgh , UK. 5Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine , Fuzhou , China. 6College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China; Fujian Key Laboratory of Rehabilitation of Technology, Fuzhou, China.
Conference/Journal: Front Aging Neurosci.
Date published: 2016 Feb 16
Other:
Volume ID: 8 , Pages: 25 , Special Notes: doi: 10.3389/fnagi.2016.00025. eCollection 2016. , Word Count: 238
Previous studies provide evidence that aging is associated with the decline of memory function and alterations in the hippocampal (HPC) function, including functional connectivity to the medial prefrontal cortex (mPFC). In this study, we investigated if longitudinal (12-week) Tai Chi Chuan and Baduanjin practice can improve memory function and modulate HPC resting-state functional connectivity (rs-FC). Memory function measurements and resting-state functional magnetic resonance imaging (rs-fMRI) were applied at the beginning and the end of the experiment. The results showed that (1) the memory quotient (MQ) measured by the Wechsler Memory Scale-Chinese Revision significantly increased after Tai Chi Chuan and Baduanjin practice as compared with the control group, and no significant difference was observed in MQ between the Tai Chi Chuan and Baduanjin groups; (2) rs-FC between the bilateral hippocampus and mPFC significantly increased in the Tai Chi Chuan group compared to the control group (also in the Baduanjin group compared to the control group, albeit at a lower threshold), and no significant difference between the Tai Chi Chuan and Baduanjin groups was observed; (3) rs-FC increases between the bilateral hippocampus and mPFC were significantly associated with corresponding memory function improvement across all subjects. Similar results were observed using the left or right hippocampus as seeds. Our results suggest that both Tai Chi Chuan and Baduanjin may be effective exercises to prevent memory decline during aging.
KEYWORDS: Baduanjin exercise; Tai Chi Chuan exercise; aging; hippocampus; medial prefrontal cortex; memory function
PMID: 26909038 [PubMed]