Author: Lewicka M1, Henrykowska GA1, Pacholski K2, Śmigielski J3, Rutkowski M4, Dziedziczak-Buczyńska M1, Buczyński A1.
Affiliation: 1Department of Epidemiology and Public Health, Medical University of Lodz, Lodz, Poland. 2Institute of Electrical Engineering System, Technical University of Lodz, Lodz, Poland. 3Department of Computer Science and Medical Statistics, Medical University of Lodz, Lodz, Poland. 4Department of Military Toxicology and Radiological Protection, Medical University of Lodz, Lodz, Poland.
Conference/Journal: Arch Med Sci.
Date published: 2015 Dec 10
Other:
Volume ID: 11 , Issue ID: 6 , Pages: 1330-9 , Special Notes: doi: 10.5114/aoms.2015.56362. , Word Count: 302
Abstract
INTRODUCTION:
Research studies carried out for decades have not solved the problem of the effect of electromagnetic radiation of various frequency and strength on the human organism. Due to this fact, we decided to investigate the changes taking place in human blood platelets under the effect of electromagnetic radiation (EMR) emitted by LCD monitors.
MATERIAL AND METHODS:
The changes of selected parameters of oxygen metabolism were measured, i.e. reactive oxygen species concentration, enzymatic activity of antioxidant defence proteins - superoxide dismutase (SOD-1) and catalase (CAT) - and malondialdehyde concentration (MDA). A suspension of human blood platelets was exposed to electromagnetic radiation of 1 kHz frequency and 150 V/m and 220 V/m intensity for 30 and 60 min. The level of changes of the selected parameters of oxidative stress was determined after the exposure and compared to the control samples (not exposed).
RESULTS:
The measurements revealed an increase of the concentration of reactive oxygen species. The largest increase of ROS concentration vs. the control sample was observed after exposure to EMF of 220 V/m intensity for 60 min (from x = 54.64 to x = 72.92). The measurement of MDA concentration demonstrated a statistically significant increase after 30-min exposure to an EMF of 220 V/m intensity in relation to the initial values (from x = 3.18 to x = 4.41). The enzymatic activity of SOD-1 decreased after exposure (the most prominent change was observed after 60-min and 220 V/m intensity from x = 3556.41 to x = 1084.83). The most significant change in activity of catalase was observed after 60 min and 220 v/m exposure (from x = 6.28 to x = 4.15).
CONCLUSIONS:
The findings indicate that exposure to electromagnetic radiation of 1 kHz frequency and 150 V/m and 220 V/m intensity may cause adverse effects within blood platelets' oxygen metabolism and thus may lead to physiological dysfunction of the organism.
KEYWORDS:
LCD monitors; catalase; malondialdehyde; reactive oxygen species; superoxide dismutase
PMID: 26788099