Electroacupuncture on PC6 prevents opioid-induced nausea and vomiting after laparoscopic surgery. Author: Lee S, Lee MS, Choi DH, Lee SK. Affiliation: Korea Institute of Oriental Medicine, University of Science and Technology Daejeon, Daejeon, South Korea. Conference/Journal: Chin J Integr Med. Date published: 2013 Apr Other: Volume ID: 19 , Issue ID: 4 , Pages: 277-81 , Special Notes: doi: 10.1007/s11655-013-1425-7 , Word Count: 214 OBJECTIVE: To investigate the treatment time dependence of electroacupuncture (EA) on Neiguan (PC6) for preventing postoperative nausea and vomiting (PONV). METHODS: One hundred and seventy-eight patients, who had received intravenous patient-controlled analgesia (PCA) with Fentanyl, were assigned randomly to three groups using random numbers: a pre-operative EA group (PrEA), a post-operative EA group (PoEA), and a non-acupuncture control group (NC). An anesthetist evaluated the incidence and severity of nausea and vomiting for 48 h after surgery blindly. The main outcomes were severity and freguency of PONV, which were measured with a self-reported questionnaire and a confirmation from the anesthetist. The data were analyzed with ANOVA and Z-test. RESULTS: The incidence of nausea and vomiting was significantly lower in the PrEA group than the NC group during 48 h after surgery (P<0.01, P<0.05). The incidence of vomiting was also significantly lower in the PrEA group than the PoEA group (P<0.05). The PoEA subjects evidenced no significant differences compared with the NC subjects in terms of the incidence of nausea and vomiting (P<0.05). The severity of nausea was significantly lower in the PrEA group than in the NC and PoEA groups (P<0.05). CONCLUSIONS: EA on PC6 is effective in the prevention of PONV, and pre-operative acupuncture is more effective than post-operative acupuncture. PMID: 23546631