Large-scale brain networks in affective and social neuroscience: towards an integrative functional architecture of the brain. Author: Barrett LF, Satpute AB. Affiliation: Northeastern University, Massachusetts General Hospital/Harvard Medical School, United States. Electronic address: l.barrett@neu.edu. Conference/Journal: Curr Opin Neurobiol. Date published: 2013 Jan 22 Other: Pages: S0959-4388(13)00017-2. , Special Notes: doi: 10.1016/j.conb.2012.12.012 , Word Count: 111 Understanding how a human brain creates a human mind ultimately depends on mapping psychological categories and concepts to physical measurements of neural response. Although it has long been assumed that emotional, social, and cognitive phenomena are realized in the operations of separate brain regions or brain networks, we demonstrate that it is possible to understand the body of neuroimaging evidence using a framework that relies on domain general, distributed structure-function mappings. We review current research in affective and social neuroscience and argue that the emerging science of large-scale intrinsic brain networks provides a coherent framework for a domain-general functional architecture of the human brain. Copyright © 2013 Elsevier Ltd. All rights reserved. PMID: 23352202