Effects of low-intensity pulsed ultrasound on autogenous bone graft healing. Author: Fındık Y, Baykul T. Affiliation: Research Assistant Doctor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Süleyman Demirel University, Isparta, Turkey. Electronic address: yavuzfindik32@hotmail.com. Conference/Journal: Oral Surg Oral Med Oral Pathol Oral Radiol. Date published: 2012 Sep 28 Other: Pages: pii: S2212-4403(12)00434-8 , Special Notes: doi: 10.1016/j.oooo.2012.05.023. , Word Count: 142 OBJECTIVE: Pulsed ultrasonic waves have been shown to accelerate bone healing. The aim of this study was to evaluate the effects of low-intensity pulsed ultrasound on bone healing. STUDY DESIGN: Thirty-two femurs from 16 skeletally mature male Wistar albino rats were used. Two defects were produced in each femur with a 3-mm-diameter trephine bur and then autogenous cortical grafts were placed in 1 defect. The animals in the experiment group received a daily 20-minute ultrasound treatment for 15 days. All animals were killed on the 18th postoperative day. RESULTS: Dual-energy x-ray absorptiometry values and biochemical markers in the experimental side were significantly higher than those in the control side at the early period of bone healing. CONCLUSIONS: Low-intensity pulsed ultrasound treatment accelerates bone healing both in bone defects and in bone defects filled with cortical autogenous block graft. Copyright © 2012 Elsevier Inc. All rights reserved. PMID: 23026154