Cortical plasticity and brain computer interface. Author: Rossini PM, Noris Ferilli MA, Ferreri F. Affiliation: Department of Neurology, Catholic University, Rome, Italy - paolomaria.rossini@afar.it. Conference/Journal: Eur J Phys Rehabil Med. Date published: 2012 Jun Other: Volume ID: 48 , Issue ID: 2 , Pages: 307-12 , Word Count: 167 There is increasing evidence to support the concept that adult brain has the remarkable ability to plastically reorganize itself. Brain plasticity involves distinct functional and structural components and plays a crucial role in reorganizing central nervous system's networks after any lesion in order to partly or totally restore lost and/or compromised functions. The idea that a computer can decode brain electromagnetic signals to infer the intentions of a human and then enact those intentions directly through a machine is becoming a reasonable technical possibility. In neurological patients unable to move and to communicate with the external environment, technologies implementing brain-machine interfaces (BMIs) can be of valuable aid and support. The emerging possibility, through neuro-imaging advanced techniques, to clarify some crucial issues underlying brain plasticity will give the possibility to modulate these mechanisms in a BCI-oriented way. This approach may have a tremendous impact in a variety of neuropsychiatric disorders and the clinical advent of this technology will usher in a new era of restorative medicine. PMID: 22614891