Effects of electromagnetic fields on bone regeneration in experimental and clinical studies: a review of the literature. Author: Zhong C, Zhao TF, Xu ZJ, He RX. Affiliation: Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, China. Conference/Journal: Chin Med J (Engl). Date published: 2012 Jan Other: Volume ID: 125 , Issue ID: 2 , Pages: 367-72 , Word Count: 137 OBJECTIVE: To assess the experimental and clinical data regarding the effects of electromagnetic fields (EMFs) on fracture non-union. DATA SOURCES: The English language literature regarding EMFs on fracture non-union were searched using MEDLINE, Web of Science and Embase, for the period January 2006 to June 2011. The search terms were electromagnetic fields and non-union/bone marrow stem cells (BMSCs)/bone. STUDY SELECTION: Articles were included in the review if they were related to the use of EMFs on BMSCs or bone tissue. Papers without full manuscripts available were excluded. RESULTS: The basic and clinical research in this field, while somewhat limited, supports the insightful application of EMFs to ameliorate disability due to fracture non-union. CONCLUSIONS: Further basic and clinical research to validate the use of EMFs in facilitating function and bone reparative processes in fracture non-union is required. PMID: 22340573