Modified action of emitted qi on rat axonal sodium channels


Author: Liu Anxi//Zhao Jing//Shong Changling//Wang Xishang

Affiliation: Dept Biology, Nankai University, China [1] 
Conference/Journal: 3rd Nat Acad Conf on Qigong Science
Date published: 1990
Other:
  Pages: 43   ,  Word Count: 227  
    The excitatory effects of emitted qi were tested on the isolated giant axon of rat, using microelectrode and oil-gap, single-fibre, voltage-clamp recording technique. The excitable activity of emitted qi primarily determined by both sodium currents, I sub Na, and delayed rectifier potassium currents, I sub K.

1. In voltage clamp, a typical current pattern associated during 10 mV step depolorization of membrane potential contained a brief emitted qi capacitative current, a transient phase of inward current(I sub Na) and a delayed maintained outward currents (I sub K). When emitted qi was applied with right hand at distance 1.2m, no change in I sub Na for 5 min, but, 6-10 min later the peak of the inward sodium current raised to -0.7 muA.cm^2 (control -0.45 A.cm)

2. Thus qigong induces a slow reversible depolarization. The emitted qi modifies sodium channels, holding them in a modifies open-state for prolonged periods (0.9-1.4 ms in experimental group control 0.7-lms). As more channels became modified in this way the axon depolarizes eventually slowing the turn-off the sodium current. Because the excitatory actions of emitted qi may be explained by an increase in sodium ions permeability.

3. Families of potassium currents were recorded and voltage-current relation were obtained before and after application of emitted qi, increased the peak current by more than 39.7% (Fig.2). It was to generate rapid depolarizations of the resting membrane for excitations.