The effects of centrally acting drugs on the EEG correlates of meditation. 
Source


Author: Sim MK//Tsoi WF

Affiliation: Faculty of Medicine, National University of Singapore
Conference/Journal: Biofeedback & Self Regulation 
Date published: 1992
Other:
 Volume ID: 17   ,  Issue ID: 3   ,  Pages: 215-20   ,  Word Count: 135  
    The present study investigated the effects of three centrally acting drugs on the significant increase in the intermediate alpha frequency of the electroencephalogram (EEG) that accompanied meditation in a male volunteer. When compared to the EEG recorded before each of the three drugs was administered, naloxone tended to enhance the increase in the power of the intermediate alpha EEG (9.4-10.4 Hz), while diazepam tended to spread the increase to the slow (7.4-9.4 Hz) alpha EEG, and flumazenil was without much effect on the overall EEG pattern. However, these EEG changes when compared to sim ilar changes obtained with saline administration were not significantly different from the latter. Thus, it is unlikely that the EEG correlates of meditation are causally related to the rise or fall of endogenous opioid peptides or benzodiazepinelike substances in the brain.