Dependable approaches to hypertension management: A review Author: Chukwuka Elendu1, Dependable C Amaechi2, Tochi C Elendu3, Emmanuel C Amaechi4, Ijeoma D Elendu3 Affiliation: <sup>1</sup> Federal University Teaching Hospital, Owerri, Nigeria. <sup>2</sup> Igbinedion University, Okada, Nigeria. <sup>3</sup> Imo State University, Owerri, Nigeria. <sup>4</sup> Madonna University, Elele, Nigeria. Conference/Journal: Medicine (Baltimore) Date published: 2024 Jun 14 Other: Volume ID: 103 , Issue ID: 24 , Pages: e38560 , Special Notes: doi: 10.1097/MD.0000000000038560. , Word Count: 199 Hypertension, a prevalent chronic condition characterized by elevated blood pressure, is a significant global health burden, contributing to approximately 7.5 million premature deaths annually. While existing literature predominantly focuses on conventional treatment modalities, this paper offers unique insights into dependable approaches to hypertension management. Drawing upon epidemiological data, it highlights the increasing prevalence of hypertension across diverse populations, emphasizing demographic disparities and regional variations. This article underscores the need for tailored interventions considering individual risk profiles and socioeconomic determinants. Beyond conventional lifestyle modifications and pharmacological therapies, it explores emerging trends such as mindfulness-based interventions and integrative medicine in hypertension management. Additionally, it discusses the role of digital health technologies and telemedicine in enhancing patient engagement and remote monitoring, optimizing treatment outcomes. Furthermore, the paper addresses the evolving landscape of personalized medicine and genomic advancements in predicting individual responses to antihypertensive therapies, advocating for precision medicine approaches. This paper advocates for a holistic and patient-centered approach to hypertension management by offering a comprehensive overview of established and emerging strategies. It underscores the importance of interdisciplinary collaboration, continuous education, and innovative research endeavors to address the multifaceted challenges posed by hypertension and improve global cardiovascular health outcomes. PMID: 38875433 PMCID: PMC11175961 DOI: 10.1097/MD.0000000000038560