Whole body vibration therapy and cognitive functions: a systematic review Author: Nisha Shantakumari1,2, Musaab Ahmed1,2 Affiliation: <sup>1</sup> College of Medicine, Ajman University, Ajman, United Arab Emirates. <sup>2</sup> Center of Medical and Bio-allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates. Conference/Journal: AIMS Neurosci Date published: 2023 May 18 Other: Volume ID: 10 , Issue ID: 2 , Pages: 130-143 , Special Notes: doi: 10.3934/Neuroscience.2023010. , Word Count: 198 Whole Body Vibration has been found to induce physiological changes in human subjects, improving their neuromuscular, respiratory and cardiovascular functions. Evidence from animal research prove that whole-body vibration appears to induce changes in molecular and cellular levels to alter cognitive functions in mice. There is evolving evidence for a potential value of whole body vibration in improving cognition and preventing the development of age-related cognitive disorders in humans. However, literature on the biological consequences of whole-body vibration on the human brain is scanty. If so, gathering the available evidences would help decide the possibility of designing appropriate whole-body vibration protocols to extend its application to induce neurocognitive enhancement and optimize its effects. Therefore, a systematic review of the literature was performed, consulting the ProQuest, MEDLINE and Scopus bibliographic databases, to summarize the available scientific evidence on the effects of whole-body vibration on cognitive functions in adults. Results of the review suggest that whole-body vibration therapy enhances a wide spectrum of cognitive functions in adults although there isn't enough evidence available yet to be able to design a standardized protocol to achieve optimum cognitive enhancement. Keywords: cognition; cognitive tests; neurocognition; vibration; whole body vibration. PMID: 37426779 PMCID: PMC10323263 DOI: 10.3934/Neuroscience.2023010