Regulation of breathing by cardiopulmonary afferents


Author: Jerry Yu1

Affiliation: <sup>1</sup> Department of Medicine (Pulmonary), University of Louisville, and Robley Rex VA Medical Center, Louisville, KY, United States. Electronic address: j0yu0001@louisville.edu.
Conference/Journal: Handb Clin Neurol
Date published: 2022 Aug 15
Other:
 Volume ID: 188   ,  Pages: 233-278   ,  Special Notes: doi: 10.1016/B978-0-323-91534-2.00014-X.   ,  Word Count: 97  
    This chapter broadly reviews cardiopulmonary sympathetic and vagal sensors and their reflex functions during physiologic and pathophysiologic processes. Mechanosensory operating mechanisms, including their central projections, are described under multiple sensor theory. In addition, ways to interpret evidence surrounding several controversial issues are provided, with detailed reasoning on how conclusions are derived. Cardiopulmonary sensory roles in breathing control and the development of symptoms and signs and pathophysiologic processes in cardiopulmonary diseases (such as cough and neuroimmune interaction) also are discussed.



Keywords: Breathing control; Chemosensitive receptors; Mechanoreceptors; Sympathetic afferent; Vagal afferent.



PMID: 35965028 DOI: 10.1016/B978-0-323-91534-2.00014-X