Biofeedback therapy combined with Baduanjin on quality of life and gastrointestinal hormone level in patients with colorectal cancer Author: Xiao-Ding Zhou1, Hong-Gang Wei2, Fu-Lu Ai3 Affiliation: <sup>1</sup> Graduate Work Department, Shenyang Sport University, Shenyang 110102, Liaoning Province, China. <sup>2</sup> Wushu and Dance Academy, Shenyang Sport University, Shenyang 110115, Liaoning Province, China. weihonggang369@163.com. <sup>3</sup> Department of General Surgery, Liaoning Tumor Hospital, Shenyang 110042, Liaoning Province, China. Conference/Journal: World J Gastrointest Oncol Date published: 2022 Jun 15 Other: Volume ID: 14 , Issue ID: 6 , Pages: 1187-1198 , Special Notes: doi: 10.4251/wjgo.v14.i6.1187. , Word Count: 353 Background: With the change in people's lifestyles, the incidence of colorectal cancer (CRC) is increasing. It is essential to study the efficacy of various treatment methods for CRC patients to prevent and treat CRC. Aim: To investigate the efficacy of biofeedback therapy combined with Baduanjin in improving the quality of life and gastrointestinal hormone levels of patients with CRC. Methods: A total of 120 patients with CRC who were admitted to our hospital from June 2020 to June 2021 were included in the study. They were randomly divided into four groups (n = 30): the control group (group A), the biofeedback therapy intervention group (group B), the Baduanjin exercise intervention group (group C), and the combination group (group D). Patients in group A adopted the standard nursing mode and necessary health education. Patients in group B were treated with biofeedback therapy based on routine nursing care. Patients in group C were given Baduanjin intervention for 12 wk based on conventional drug treatment and care. Patients in group D were treated with biofeedback therapy and Baduanjin exercise. In this study, patients' quality of life, gastrointestinal hormone levels, and clinical efficacy in the four groups were observed at baseline and 12 wk after intervention. Meanwhile, the correlation between gastrointestinal hormone levels and various functional areas of quality of life was analyzed. By comparing the observed indicators of patients in the four groups, the efficacy of biofeedback therapy combined with Baduanjin in improving the quality of life and gastrointestinal hormone levels of patients with CRC was explored. Results: At baseline, there were no significant differences in quality of life, gastrointestinal hormone levels, or clinical efficacy among the four groups (P > 0.05). Twelve weeks after the intervention, the combination group's quality of life, gastrointestinal hormone levels, and clinical effectiveness were better than those of the three other groups. Conclusion: On the basis of routine nursing care, patients with CRC combined with biofeedback therapy and Baduanjin exercise can improve the quality of life of patients with CRC and the efficacy of gastrointestinal hormone levels. Keywords: Baduanjin; Biofeedback therapy; Clinical efficacy; Colorectal cancer; Gastrointestinal hormone level; Quality of life. PMID: 35949217 PMCID: PMC9244983 DOI: 10.4251/wjgo.v14.i6.1187