Association Between Physical Exercise and Mental Health During the COVID-19 Outbreak in China: A Nationwide Cross-Sectional Study Author: Yingjun Nie1, Yuanyan Ma2, Yankong Wu3, Jiahui Li3, Ting Liu3, Ce Zhang3, Chennan Lv3, Jie Zhu4 Affiliation: <sup>1</sup> College of the Arts, Wuhan Sports University, Wuhan, China. <sup>2</sup> College of Science and Technology, Wuhan Sports University, Wuhan, China. <sup>3</sup> Graduate School, Wuhan Sports University, Wuhan, China. <sup>4</sup> College of Health Sciences, Wuhan Sports University, Wuhan, China. Conference/Journal: Front Psychiatry Date published: 2021 Aug 16 Other: Volume ID: 12 , Pages: 722448 , Special Notes: doi: 10.3389/fpsyt.2021.722448. , Word Count: 324 The COVID-19 has undergone several mutations, and caused deleterious effects on physical and mental health of people worldwide. Whilst physical exercise is known for its positive effect on enhancing immunity and reducing the negative consequences of unhealthy emotional states caused by the pandemic; there is a severe lack of psychological exercise intervention measures and mitigation strategies to advance the knowledge and role of physical exercise to improve mental health in most countries. This study surveyed the association between physical exercise and mental health burden during the COVID-19 outbreak in China to better understand the influence of different physical exercise types on reducing mental health burden during the pandemic. ANOVA, binary logistic regression, the chi-square test, and Spearman's correlation analysis were used for statistical analysis. 14,715 participants were included. The results showed that Chinese residents had several poor mental health conditions during the COVID-19 outbreak. And there was a significant positive correlation between the extent of adverse effects on mental health and provincial proportions of confirmed COVID-19 cases (r = 0.365, p < 0.05). Some main factors caused an unhealthy psychological status, including epidemic severity (62.77%, 95% CI 58.62-65.64%), prolonged home quarantine (60.84%, 95% CI 58.15-63.25%), spread of large amounts of negative information about COVID-19 in the media (50.78%, 95% CI 47.46-53.15%), limitations in daily life and social interaction (45.93%, 95%CI 42.46-47.55%), concerns about students' learning (43.13%, 95% CI 40.26-45.48%), and worries about being infected (41.13%, 95% CI 39.16-45.23%). There was a significant association between physical exercise and mental health. The largest associations were seen for home-based group entertainment exercise (i.e., family games, rope skipping, and badminton), Chinese traditional sports (i.e., Chinese martial arts, Taijiquan and Qigong), and popular sports (i.e., yoga, video dancing, sensory-motor games, and whole-body vibration), as well as durations of 30-60 min per session, frequencies of three to five times per week and a total of 120-270 min of moderate-intensity exercise weekly during the COVID-19 outbreak (p < 0.05). Keywords: COVID-19; Chinese residents; home quarantine; mental health; physical exercise. PMID: 34489763 PMCID: PMC8418057 DOI: 10.3389/fpsyt.2021.722448