The Fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future Author: Timir Datta-Chaudhuri1, Theodoros Zanos1, Eric H Chang1, Peder S Olofsson2, Stephan Bickel1, Chad Bouton1, Daniel Grande1, Loren Rieth1,3, Cynthia Aranow1, Ona Bloom1, Ashesh D Mehta1, Gene Civillico4, Molly M Stevens5, Eric Głowacki6, Christopher Bettinger7, Martin Schüettler8, Chris Puleo9, Robert Rennaker10, Saroj Mohanta11, Daniela Carnevale12,13, Silvia V Conde14, Bruno Bonaz15, David Chernoff16, Suraj Kapa17, Magnus Berggren6, Kip Ludwig18, Stavros Zanos1, Larry Miller1, Doug Weber7, Daniel Yoshor19, Lawrence Steinman20, Sangeeta S Chavan21, Valentin A Pavlov22, Yousef Al-Abed23, Kevin J Tracey24 Affiliation: <sup>1</sup> The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. <sup>2</sup> Karolinska Institute, Solna, Sweden. <sup>3</sup> University of Utah, Salt Lake City, UT, USA. <sup>4</sup> National Institutes of Health, Bethesda, MD, USA. <sup>5</sup> Imperial College of London, London, UK. <sup>6</sup> Linköping University, Linköping, Sweden. <sup>7</sup> Carnegie Mellon University, Pittsburgh, PA, USA. <sup>8</sup> CorTec GmbH, Freiburg im Breisgau, Germany. <sup>9</sup> General Electric, Niskayuna, NY, USA. <sup>10</sup> University of Texas at Dallas, Richardson, TX, USA. <sup>11</sup> Institute for Cardiovascular Prevention, Ludwig-Maximilians-University, Munich, Germany. <sup>12</sup> Sapienza University of Rome, Rome, Italy. <sup>13</sup> IRCCS Neuromed, Pozzilli, Italy. <sup>14</sup> CEDOC, Nova Medical School, Faculdade de Ciências Médicas, Lisbon, Portugal. <sup>15</sup> University of Grenoble Alpes, INSERM, Grenoble, France. <sup>16</sup> SetPoint Medical, Santa Clarita, CA, USA. <sup>17</sup> Mayo Clinic, Rochester, MN, USA. <sup>18</sup> University of Wisconsin, Madison, WI, USA. <sup>19</sup> University of Pennsylvania, Philadelphia, PA, USA. <sup>20</sup> Stanford University, Stanford, CA, USA. <sup>21</sup> The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. schavan@northwell.edu. <sup>22</sup> The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. VPavlov@northwell.edu. <sup>23</sup> The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. YAlAbed@northwell.edu. <sup>24</sup> The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA. KJTracey@northwell.edu. Conference/Journal: Bioelectron Med Date published: 2021 May 24 Other: Volume ID: 7 , Issue ID: 1 , Pages: 7 , Special Notes: doi: 10.1186/s42234-021-00068-6. , Word Count: 147 There is a broad and growing interest in Bioelectronic Medicine, a dynamic field that continues to generate new approaches in disease treatment. The fourth bioelectronic medicine summit "Technology targeting molecular mechanisms" took place on September 23 and 24, 2020. This virtual meeting was hosted by the Feinstein Institutes for Medical Research, Northwell Health. The summit called international attention to Bioelectronic Medicine as a platform for new developments in science, technology, and healthcare. The meeting was an arena for exchanging new ideas and seeding potential collaborations involving teams in academia and industry. The summit provided a forum for leaders in the field to discuss current progress, challenges, and future developments in Bioelectronic Medicine. The main topics discussed at the summit are outlined here. Keywords: Bioelectronic medicine; Clinical trials; Devices; Electronics; Feinstein Institutes for Medical Research; Materials science; Neural circuits; Preclinical research; Summit; Vagus nerve stimulation. PMID: 34024277 DOI: 10.1186/s42234-021-00068-6