Traditional Chinese Medicine's liver yang ascendant hyperactivity pattern of essential hypertension and its treatment approaches: A narrative review Author: Xuhua Huang1, Sakhorn Ngaenklangdon2, Jun He3, Xiumei Gao4 Affiliation: <sup>1</sup> Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. <sup>2</sup> Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Faculty of Traditional Chinese Medicine, Nakhonratchasima College, Thailand. <sup>3</sup> Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address: hejun673@163.com. <sup>4</sup> Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address: gaoxiumei@tjutcm.edu.cn. Conference/Journal: Complement Ther Clin Pract Date published: 2021 Mar 6 Other: Volume ID: 43 , Pages: 101354 , Special Notes: doi: 10.1016/j.ctcp.2021.101354. , Word Count: 162 "Liver yang ascendant hyperactivity" (SF52), as termed by WHO, is a commonly observed pattern of essential hypertension (EH), herein referred to as EH-SF52. This paper summarizes the Traditional Chinese Medicine (TCM) perspectives, biomedical findings, and TCM managements for EH-SF52 in modern times. EH-SF52 is generally identified as an EH individual presenting with headache, dizziness, poor sleep quality, tinnitus, facial flushing, fatigue, signs of mild dehydration, and whom are highly irritable individuals with a tendency to overthink, be competitive, or be aggressive. The proposed EH-SF52 model features a state of autonomic imbalance and vascular changes that accounts for the above symptoms. TCM managements for EH-SF52 includes Chinese herbal medication, acupuncture, qigong, taichi, massage, food therapy, as well as lifestyle changes, which targets symptomatic alleviation and blood pressure reduction in a multi-mechanistic manner. An increasing shift towards integrated practice of TCM and western medicine in EH-SF52 requires effective communication between both disciplines. Keywords: Ascendant hyperactivity; Essential hypertension; Liver yang; TCM. PMID: 33706064 DOI: 10.1016/j.ctcp.2021.101354