Tai Chi for the elderly patients with COVID-19 in recovery period: A protocol for systematic review and meta-analysis Author: Xiangyu Zhu1, Ziyu Luo1, Ying Chen2, Lina Wang3, Wenxin Chi1, Lu Lian Jiang1, Ke Liu1, Liping Zhao1, Yu Zhang1, Haibo Zhang1 Affiliation: <sup>1</sup> School of Acupuncture, Moxibustion and Tuina. <sup>2</sup> Dongzhimen Hospital, Beijing University of Chinese Medicine. <sup>3</sup> Laboratory of Statistics and Measurement, Beijing Sport University, Beijing, China. Conference/Journal: Medicine (Baltimore) Date published: 2021 Jan 22 Other: Volume ID: 100 , Issue ID: 3 , Pages: e24111 , Special Notes: doi: 10.1097/MD.0000000000024111. , Word Count: 231 Background: The coronavirus disease 2019 (COVID-19) outbreak has caused a great impact in many countries. Older people are more susceptible to the virus than other people. As a good health exercise suitable for the elderly, Tai Chi has a positive impact on heart function, blood pressure, lung function, immunity, etc. It can enhance cardiopulmonary function, increase the elasticity of blood vessels, and improve the body's self-regulation function. For the elder patients with COVID-19, Tai Chi has outstanding merits. Methods: We will search PubMed, EMBASE, MEDLINE, the Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Database, Wanfang Database, Clinical Trials and Chinese Clinical Trial Registry. The complete process will include study selection, data extraction, risk of bias assessment and meta-analyses. Endnote X9.3 will be used to manage data screening. The statistical analysis will be completed by Stata/SE 15.1 software. Results: This proposed study will evaluate the effectiveness and safety of Tai Chi for the improvement of psychological pressure, cardiopulmonary function, and immunity in elderly COVID-19 patients during the recovery period. Conclusion: The conclusion of this study will provide evidence to prove the safety and effectiveness of Tai Chi on elderly COVID-19 patients during the recovery period. Ethics and dissemination: This protocol will not evaluate individual patient information or infringe patient rights and therefore does not require ethical approval. Registration: PEROSPERO CRD42020220128. PMID: 33546018 PMCID: PMC7837887 DOI: 10.1097/MD.0000000000024111