Baduanjin exercise intervention for community adults at risk of ischamic stroke: A randomized controlled trial Author: Guohua Zheng1,2, Bai Chen2, Qianying Fang2, Qiu Lin3, Jing Tao4, Lidian Chen5 Affiliation: <sup>1</sup> College of Nursing and Health Management, Shanghai University of Medicine &amp; Health Sciences, Shanghai, 201318, China. <sup>2</sup> College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. <sup>3</sup> Department of Physical Education, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. <sup>4</sup> Fujian Key Laboratory of Rehabilitation Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. <sup>5</sup> Collaborative Innovation Center for Rehabilitation Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. cld@fjtcm.edu.cn. Conference/Journal: Sci Rep Date published: 2019 Feb 4 Other: Volume ID: 9 , Issue ID: 1 , Pages: 1240 , Special Notes: doi: 10.1038/s41598-018-37544-0. , Word Count: 220 The aim of current study was to assess the effects of Baduanjin exercise on cerebrovascular function, cardiac structure and cardiac function, static pulmonary function, traditional risk factors of CVD and the related psychological outcomes in older community adults at risk for ischaemic stroke. A randomized controlled trial was conducted in three community between November 2013 and October 2015. Older community-dwelling adults (N = 170) were randomly allocated into either a Baduanjin training (5 × 60 min/weekly) or control group who kept their unaltered lifestyle during a 12-week intervention period. Primary (cerebral haemodynamic parameters) and secondary outcomes (cardiac structure, cardiac function, static pulmonary function, traditional risk factors and the related psychological outcomes) were measured at baseline, after a 12-week intervention period and after an additional 12-week follow-up period. After the 12-week intervention period and additional 12-week follow-up period, the Baduanjin exercise group displayed significant changes in most cerebral haemodynamic parameters compared to the control group: lower systolic blood pressure, diastolic blood pressure, plasma total cholesterol levels, waist circumference, hip circumference and waist/hip ratio; and improved mood, self-confidence, self-esteem, quality of life and sleep quality. A supervised 12-week Baduanjin exercise intervention was effective and safe in modulating cerebral haemodynamics, reducing blood pressure and improving anthropometric parameters and related psychological outcomes in older community adults at risk for ischaemic stroke. PMID: 30718622 PMCID: PMC6362011 DOI: 10.1038/s41598-018-37544-0