Early Post-Operative Intervention of Whole-Body Vibration in Patients After Total Knee Arthroplasty: A Pilot Study. Author: Hsiao YH1, Chien SH2, Tu HP3, Fu JC1, Tsai ST1, Chen YS1, Chen YJ1,4,5, Chen CH1,4,6,7 Affiliation: <sup>1</sup>Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. <sup>2</sup>Department of Orthopaedics, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. <sup>3</sup>Department of Public Health and Environmental Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. <sup>4</sup>Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. <sup>5</sup>Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. <sup>6</sup>Department of Physical Medicine and Rehabilitation, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 801, Taiwan. <sup>7</sup>Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Conference/Journal: J Clin Med. Date published: 2019 Nov 7 Other: Volume ID: 8 , Issue ID: 11 , Special Notes: doi: 10.3390/jcm8111902. , Word Count: 215 (1) Background: Knee osteoarthritis causes pain, weakness, muscle atrophy, and disability. The application of whole-body vibration in patients with knee osteoarthritis can improve strength, balance, and functional activities. The purpose of the study is to evaluate the effects of early whole-body vibration intervention in patients after total knee arthroplasty. (2) Method: A single-blinded randomized control trial. Fifty-two patients with knee osteoarthritis post total knee replacement from a medical center in southern Taiwan were randomly assigned to either a whole-body vibration group or control group. Main outcome measures included pain severity, leg circumference, knee range of motion, knee extensor strength, a five-times sit to stand test, and a timed up and go test. (3) Results: Immediately post treatment, the patients in the vibration group showed a significant increase in knee extensor strength and improvement in calf swelling compared to the control group. A trend toward decrease in pain severity and improvement in functional performance were observed in both groups without a significant difference between the groups. There was no significant difference in knee range of motion (ROM) and functional performance between the groups. (4) Conclusions: The whole-body vibration intervention in patients early post total knee arthroplasty showed significant immediate effect in increasing knee extensor strength and decreasing calf swelling. KEYWORDS: strength; swelling; total knee arthroplasty; whole-body vibration PMID: 31703305 DOI: 10.3390/jcm8111902