Stimulation of Protein Expression Through the Harmonic Resonance of Frequency-Specific Music.


Author: Orhan IY1, Gulbahar BA

Affiliation: <sup>1</sup>. w207725797@student.hccs.edu.
Conference/Journal: Clin Invest Med.
Date published: 2016 Dec 1
Other:
 Volume ID: 39   ,  Issue ID: 6   ,  Pages: 27498   ,  Word Count: 240  
    PURPOSE: The use of specific frequencies for specific individual amino acids may increase the potential energy of protein molecules in the medium [1]. The resonance would also increase the movement of particles in the cytosol, increasing the collisions necessary for the conduction of protein expression.



METHODS: The clash of two waves that share frequencies will exhibit an increase in energy through an increase in amplitude [2]. The increase in energy would in turn increase the number of collisions forming the tRNA-amino acid, increasing the amino acid acquiry for ribosomes to improve intracellular efficiency in gene expression. To test the hypothesis, Red Fluorescent Protein (RFP) in transformated BL-21 strains of E. coli and p53 protein of MCF-7 were examined after exposure to sounds of specific frequencies.



RESULTS: Through the exposure of the experimental systems to a sequence of sounds that match the frequencies of specific amino acids, the levels of RFP exhibition respective to the control groups in the bacterial medium increased two-fold in terms of RFU. The experiments that targeted the p53 protein with the 'music' showed a decrease in the cell prevalence in the MCF-7 type breast cancer cells by 28%, by decreasing the speed of tumour formation.



CONCLUSION: Exposure to 'music' that was designed through assigning a musical note for every single one of the twenty unique amino acids, produced both an analytical and a visible shift in protein synthesis, making it as potential tool for reducing procedural time uptake.



PMID: 27917789