Role of the Whole Body Vibration Machine in the Prevention and Management of Osteoporosis in Old Age: A Systematic Review. Author: Swe M1, Benjamin B2, Tun AA3, Sugathan S4 Affiliation: <sup>1</sup>Orthopaedic Unit, Surgical-based Department, University Kuala Lumpur, Royal College of Medicine Perak, Jalan Green town, 30450 Ipoh, Perak, Malaysia. <sup>2</sup>Department of Orthopaedics, University Kuala Lumpur, Royal College of Medicine Perak, Jalan Green town, 30450 Ipoh, Perak, Malaysia. <sup>3</sup>Department of Pathology, University Kuala Lumpur, Royal College of Medicine Perak, Jalan Green town, 30450 Ipoh, Perak, Malaysia. <sup>4</sup>Department of Public Health, University Kuala Lumpur, Royal College of Medicine Perak, Jalan Green town, 30450 Ipoh, Perak, Malaysia. Conference/Journal: Malays J Med Sci. Date published: 2016 Sep Other: Volume ID: 23 , Issue ID: 5 , Pages: 8-16 , Word Count: 201 A literature search of related articles was carried out in electronic data sources. Initially, 276 randomised controlled trials related to the title were collected, after which 44 were selected using the keywords. Overlapping articles, articles with a study duration of less than six months, and studies involving young participants were removed from the list. The remaining 20 articles were checked for entitlement using the PEDro scale. A total of nine eligible articles with 1486 participants were analysed. Seven trials used dual-energy x-ray absorptiometry (DXA) to measure bone mineral density (BMD). The six trials published from 2005 to 2013 found a significant increase in BMD. In the remaining one trial, there was no significant increase in BMD. One study published in 2013 reported a significant increase in BMD measured with peripheral qualitative computed tomography, whereas another trial published in 2014 stated that there was a reduction in calcaneal bone density measured by peripheral qualitative ultrasound. From these findings it can be concluded that the whole body vibration machine is a good adjunctive therapy for the prevention and management of osteoporosis in postmenopausal women. However, further investigations are necessary before the same can be recommended for elderly men. KEYWORDS: bone mineral density (BMD); elderly; osteoporosis; vibration PMID: 27904420 PMCID: PMC5101982 DOI: 10.21315/mjms2016.23.5.2