Effect of long-term pulsed electromagnetic field exposure on hepatic and immunologic functions of rats.


Author: Li BL1, Li W, Bi JQ, Zhao JG, Qu ZW, Lin C, Yang SL, Meng QG, Yue Q.

Affiliation: 1Department of Orthopaedic Surgery, The First Hospital of Harbin City, Harbin Medical University, No. 149, Mai Mai Street, Dao Li District, 150001, Harbin, Heilongjiang Province, China.
Conference/Journal: Wien Klin Wochenschr.
Date published: 2015 Apr 25
Other:
  Word Count: 126  
    

BACKGROUND:

In this report, the effects of long-term pulsed electromagnetic field (PEMF) exposure on hepatic and immunologic functions were examined.

METHODS:

Male rats were randomly divided into four groups: a control group and three experimental groups exposed to a 50-Hz PEMF at 5, 10, or 20 mT for 10 weeks.

RESULTS:

Compared with the control group, activities of serum alanine aminotransferase and aspartate aminotransferase and concentrations of serum, liver, and spleen Metabolism of lipid peroxidation (MDA) in the 10- and 20-mT PEMF groups were significantly increased. The activities of Glutathione peroxidase (GSH-Px) and Superoxide Dismutase (SOD) in the serum, liver, and spleen and concentrations of serum immunoglobulins were significantly decreased.

CONCLUSION:

These results demonstrate that long-term exposure to PEMF can lead to oxidative damage of the liver and spleen.

PMID: 25910613