What is the Role of Alternative Treatments in Late-life Depression? Author: Nyer M, Doorley J, Durham K, Yeung AS, Freeman MP, Mischoulon D. Affiliation: Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA. Electronic address: mnyer@partners.org. Conference/Journal: Psychiatr Clin North Am. Date published: 2013 dec Other: Volume ID: 36 , Issue ID: 4 , Pages: 577-96 , Special Notes: doi: 10.1016/j.psc.2013.08.012 , Word Count: 93 Late-life depression remains challenging to treat. One major limitation to treatment is the concern over medication-related side effects to which the elderly are especially vulnerable. Also, because many elderly people are already taking multiple medications for medical conditions, there is the concern over drug-drug interactions. This article reviews various complementary and alternative medicine interventions for late-life depression, including natural remedies, exercise, yoga, tai chi, massage therapy, music therapy, and religion and spirituality. Copyright © 2013 Elsevier Inc. All rights reserved. KEYWORDS: Exercise, Late-life depression, Massage therapy, Music therapy, Natural remedies, Spirituality, Tai chi, Yoga PMID: 24229658